Item no. |
ABC-ABO11207 |
Manufacturer |
Abcepta
|
Amount |
100 ug |
Category |
|
Type |
Antibody Primary |
Format |
Lyophilized |
Applications |
WB, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
TXNRD2, mitochondrial, TRXR2, Thioredoxin reductase 2, Selenoprotein Z, SelZ, TR-beta, Thioredoxin reductase TR3, KIAA1652, 1.8.1.9 |
Available |
|
Primary Accession |
Q9NNW7 |
Application |
WB, IHC-P |
Clonality |
Polyclonal |
Gene ID |
10587 |
Reactivity |
H, Rat |
Legend image 1 |
Anti-TXNRD2 antibody, ABO11207, Western blottingLane 1: Rat Kidney Tissue LysateLane 2: Rat Ovary Tissue LysateLane 3: Rat Liver Tissue LysateLane 4: SMMC Cell Lysate |
Type image 1 |
WB |
Dilution image 1 |
0.1-0.5 µg/ml |
Legend image 2 |
Anti-TXNRD2 antibody, ABO11207, IHC(P)IHC(P): Human Lung Cancer Tissue |
Type image 2 |
IHC |
Dilution image 2 |
0.5-1 µg/ml |
Calculated MW |
56507 |
Reconstitution |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Description |
Rabbit IgG polyclonal antibody for Thioredoxin reductase 2, mitochondrial(TXNRD2) detection. Tested with WB, IHC-P in Human; Rat. |
Protein Function |
Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox- regulated cell signaling. |
Subcellular Localization |
Mitochondrion . |
Tissue Specificity |
Highly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614, levels are low. . |
Protein Name |
Thioredoxin reductase 2, mitochondrial |
Contents |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
Immunogen |
A synthetic peptide corresponding to a sequence at the C-terminus of human TXNRD2(418-434aa RHGQEHVEVYHAHYKPL), different from the related rat sequence by three amino acids, and from the related mouse sequence by two amino acids. |
Purification |
Immunogen affinity purified. |
Cross Reactivity |
No cross reactivity with other proteins |
Storage |
At -20?C for one year. After r?Constitution, at 4?C for one month. It?Can also be aliquotted and stored frozen at -20?C for a longer time.Avoid repeated freezing and thawing. |
Concentration (mg/ml) |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Sequence Similarities |
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.