Item no. |
ABC-ABO10942 |
Manufacturer |
Abcepta
|
Amount |
100 ug |
Category |
|
Type |
Antibody Primary |
Format |
Lyophilized |
Applications |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
JAK1, Tyrosine-protein kinase JAK1, Janus kinase 1, JAK1A, JAK1B, JAK-1, 2.7.10.2 |
Available |
|
Primary Accession |
P23458 |
Application |
WB |
Clonality |
Polyclonal |
Gene ID |
3716 |
Reactivity |
H, M, Rat |
Legend image 1 |
Anti- JAK1 antibody, ABO10942, Western blottingAll lanes: Anti JAK1 (ABO10942) at 0.5ug/mlLane 1: U87 Whole Cell Lysate at 40ugLane 2: MM231 Whole Cell Lysate at 40ugLane 3: SW620 Whole Cell Lysate at 40ugPredicted bind size: 133KDObserved bind size: 133KD |
Type image 1 |
WB |
Dilution image 1 |
0.1-0.5 µg/ml |
Calculated MW |
133277 |
Reconstitution |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Description |
Rabbit IgG polyclonal antibody for Tyrosine-protein kinase JAK1(JAK1) detection. Tested with WB in Human; Mouse; Rat. |
Protein Function |
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor. . |
Subcellular Localization |
Endomembrane system; Peripheral membrane protein. Wholly intracellular, possibly membrane associated. |
Tissue Specificity |
Expressed at higher levels in primary colon tumors than in normal colon tissue. The expression level in metastatic colon tumors is comparable to the expression level in normal colon tissue. . |
Protein Name |
Tyrosine-protein kinase JAK1 |
Contents |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
Immunogen |
A synthetic peptide corresponding to a sequence at the C-terminus of human JAK1(970-984aa KNKNKINLKQQLKYA), identical to the related mouse and rat sequences. |
Purification |
Immunogen affinity purified. |
Cross Reactivity |
No cross reactivity with other proteins |
Storage |
At -20?C for one year. After r?Constitution, at 4?C for one month. It?Can also be aliquotted and stored frozen at -20?C for a longer time.Avoid repeated freezing and thawing. |
Concentration (mg/ml) |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Sequence Similarities |
Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.