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Anti-DAP Kinase 2 Antibody

Anti-DAP Kinase 2 Antibody

Item no.	ABC-ABO10876
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Lyophilized
Applications	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	DAPK2, Death-associated protein kinase 2, DAP-kinase-related protein 1, DAP kinase 2, 2.7.11.1, DRP-1
Available
Primary Accession	Q9UIK4
Application	WB
Clonality	Polyclonal
Gene ID	23604
Reactivity	H, M, Rat
Legend image 1	Anti-DAP Kinase 2 antibody, ABO10876, Western blottingAll lanes: Anti DAP Kinase 2 (ABO10876) at 0.5ug/mlLane 1: U87 Whole Cell Lysate at 40ugLane 2: MCF-7 Whole Cell Lysate at 40ugLane 3: SMMC Whole Cell Lysate at 40ugPredicted bind size: 43KDObserved bind size: 43KD
Type image 1	WB
Dilution image 1	0.1-0.5 µg/ml
Calculated MW	42898
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Description	Rabbit IgG polyclonal antibody for Death-associated protein kinase 2(DAPK2) detection. Tested with WB in Human; Mouse; Rat.
Protein Function	Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation.
Subcellular Localization	Cytoplasm. Cytoplasmic vesicle, autophagosome lumen.
Tissue Specificity	Isoform 2 is expressed in embryonic stem cells (at protein level). Isoform 1 is ubiquitously expressed in all tissue types examined with high levels in heart, lung and skeletal muscle. It is expressed abundantly in cells differentiated toward granulocytes and low in undifferentiated, normal and leukemic hematopoietic cells and monocytes/macrophages. .
Protein Name	Death-associated protein kinase 2(DAP kinase 2)
Contents	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Immunogen	A synthetic peptide corresponding to a sequence at the C-terminus of human DAP Kinase 2(289-308aa DNQQAMVRRESVVNLENFRK), different from the related mouse and rat sequences by two amino acids.
Purification	Immunogen affinity purified.
Cross Reactivity	No cross reactivity with other proteins
Storage	At -20?C for one year. After r?Constitution, at 4?C for one month. It?Can also be aliquotted and stored frozen at -20?C for a longer time.Avoid repeated freezing and thawing.
Concentration (mg/ml)	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Sequence Similarities	Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 10/4/2024

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