Item no. |
ABC-ABO10735 |
Manufacturer |
Abcepta
|
Amount |
100 ug |
Category |
|
Type |
Antibody Primary |
Format |
Lyophilized |
Applications |
WB, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
PR, PGR, NR3C3, Progesterone receptor, Nuclear receptor subfamily 3 group C member 3 |
Available |
|
Primary Accession |
P06401 |
Application |
WB, IHC-P |
Clonality |
Polyclonal |
Gene ID |
5241 |
Reactivity |
H, M, Rat |
Legend image 1 |
Anti-Progesterone Receptor antibody, ABO10735, Western blottingWB: HELA Cell Lysate |
Type image 1 |
WB |
Dilution image 1 |
0.1-0.5 µg/ml |
Legend image 2 |
Anti-Progesterone Receptor antibody, ABO10735, IHC(P)IHC(P): Human Rectal Cancer Tissue |
Type image 2 |
IHC |
Dilution image 2 |
0.5-1 µg/ml |
Calculated MW |
98981 |
Reconstitution |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Description |
Rabbit IgG polyclonal antibody for Progesterone receptor(PGR) detection. Tested with WB, IHC-P in Human; Mouse; Rat. |
Protein Function |
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. |
Subcellular Localization |
Nucleus. Cytoplasm. Nucleoplasmic shuttling is both homone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases. |
Protein Name |
Progesterone receptor(PR) |
Contents |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
Immunogen |
A synthetic peptide corresponding to a sequence in the middle region of human Progesterone Receptor(536-553aa QVYPPYLNYLRPDSEASQ), identical to the related rat and mouse sesquences. |
Purification |
Immunogen affinity purified. |
Cross Reactivity |
No cross reactivity with other proteins |
Storage |
At -20?C for one year. After r?Constitution, at 4?C for one month. It?Can also be aliquotted and stored frozen at -20?C for a longer time.Avoid repeated freezing and thawing. |
Concentration (mg/ml) |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Sequence Similarities |
Belongs to the nuclear hormone receptor family. NR3 subfamily. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.