Item no. |
ABC-ABO10512 |
Manufacturer |
Abcepta
|
Amount |
100 ug |
Category |
|
Type |
Antibody Primary |
Format |
Lyophilized |
Applications |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
CCR-5, CCR5, CMKBR5, C-C chemokine receptor type 5, CHEMR13, HIV-1 fusion coreceptor, C-C CKR-5, CC-CKR-5, CD195 |
Available |
|
Primary Accession |
P51681 |
Application |
WB |
Clonality |
Polyclonal |
Gene ID |
1234 |
Reactivity |
H |
Legend image 1 |
Anti-CCR5 antibody, ABO10512, Western blottingLane 1: COLO320 Cell LysateLane 2: MCF-7 Cell LysateLane 3: SMMC Cell LysateLane 4: JURKAT Cell Lysate |
Type image 1 |
WB |
Dilution image 1 |
0.1-0.5 µg/ml |
Calculated MW |
40524 |
Reconstitution |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Description |
Rabbit IgG polyclonal antibody for C-C chemokine receptor type 5(CCR5) detection. Tested with WB in Human. |
Protein Function |
Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates. . |
Subcellular Localization |
Cell membrane ; Multi-pass membrane protein . |
Tissue Specificity |
Highly expressed in spleen, thymus, in the myeloid cell line THP-1, in the promyeloblastic cell line KG-1a and on CD4+ and CD8+ T-cells. Medium levels in peripheral blood leukocytes and in small intestine. Low levels in ovary and lung. . |
Protein Name |
C-C chemokine receptor type 5 |
Contents |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
Immunogen |
A synthetic peptide corresponding to a sequence in the middle region of human CCR5(179-197aa SSHFPYSQYQFWKNFQTLK). |
Purification |
Immunogen affinity purified. |
Cross Reactivity |
No cross reactivity with other proteins |
Storage |
At -20?C for one year. After r?Constitution, at 4?C for one month. It?Can also be aliquotted and stored frozen at -20?C for a longer time.Avoid repeated freezing and thawing. |
Concentration (mg/ml) |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Sequence Similarities |
Belongs to the G-protein coupled receptor 1 family. |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.