Item no. |
ABC-ABO10448 |
Manufacturer |
Abcepta
|
Amount |
100 ug |
Category |
|
Type |
Antibody Primary |
Format |
Lyophilized |
Applications |
WB, ICC, IHC-P, IHC-F |
Clone |
F4 |
Specific against |
other |
Host |
Mouse |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
Multidrug resistance protein 3, P-glycoprotein 3, Mdr3, Pgy3, Abcb4, Mdr1a, Pgy-3, Multidrug resistance protein 1A, ATP-binding cassette sub-family B member 1A, Abcb1a, 3.6.3.44, MDR1A |
Available |
|
Primary Accession |
P21447 |
Application |
WB, IHC-P, IHC-F, ICC |
Clonality |
Monoclonal |
Gene ID |
18671 |
Reactivity |
H |
Isotype |
Mouse IgG1 |
Calculated MW |
140647 |
Reconstitution |
Add 1ml of PBS buffer will yield a concentration of 100ug/ml. |
Description |
Mouse IgG monoclonal antibody for P-Glycoprotein (MDR), ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1 ) detection. Tested with WB, IHC-P, IHC-F, ICC in Human. No cross reactivity with other proteins. |
Protein Function |
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. . |
Subcellular Localization |
Cell membrane; Multi-pass membrane protein. |
Tissue Specificity |
ABCB1: Expressed in liver, kidney, small intestineand brain. |
Protein Name |
Multidrug resistance protein 1 |
Contents |
Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. |
|
Clone: F4 |
Immunogen |
Mixture of human and hamster drug-resistant whole cells and crude plasma membranes. |
Purification |
Ascites |
Cross Reactivity |
No cross reactivity with other proteins |
Storage |
At -20?C for one year. After r?Constitution, at 4?C for one month. It?Can also be aliquotted and stored frozen at -20?C for a longer time.Avoid repeated freezing and thawing. |
Concentration (mg/ml) |
Add 1ml of PBS buffer will yield a concentration of 100ug/ml. |
Sequence Similarities |
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.