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Anti-P-GlycoProtein(MDR) Antibody (Monoclonal, F4)

Anti-P-GlycoProtein(MDR) Antibody (Monoclonal, F4)

Item no.	ABC-ABO10448
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Lyophilized
Applications	WB, ICC, IHC-P, IHC-F
Clone	F4
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	Multidrug resistance protein 3, P-glycoprotein 3, Mdr3, Pgy3, Abcb4, Mdr1a, Pgy-3, Multidrug resistance protein 1A, ATP-binding cassette sub-family B member 1A, Abcb1a, 3.6.3.44, MDR1A
Available
Primary Accession	P21447
Application	WB, IHC-P, IHC-F, ICC
Clonality	Monoclonal
Gene ID	18671
Reactivity	H
Isotype	Mouse IgG1
Calculated MW	140647
Reconstitution	Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Description	Mouse IgG monoclonal antibody for P-Glycoprotein (MDR), ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1 ) detection. Tested with WB, IHC-P, IHC-F, ICC in Human. No cross reactivity with other proteins.
Protein Function	Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. .
Subcellular Localization	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	ABCB1: Expressed in liver, kidney, small intestineand brain.
Protein Name	Multidrug resistance protein 1
Contents	Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
	Clone: F4
Immunogen	Mixture of human and hamster drug-resistant whole cells and crude plasma membranes.
Purification	Ascites
Cross Reactivity	No cross reactivity with other proteins
Storage	At -20?C for one year. After r?Constitution, at 4?C for one month. It?Can also be aliquotted and stored frozen at -20?C for a longer time.Avoid repeated freezing and thawing.
Concentration (mg/ml)	Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Sequence Similarities	Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 10/4/2024

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