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Anti-TLR3 Picoband Antibody

Anti-TLR3 Picoband Antibody

Item no.	ABC-ABO10038
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Lyophilized
Applications	WB, ELISA
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Primary Accession	A00197
Application	WB, E
Clonality	Polyclonal
Reactivity	H, M, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Description	Rabbit IgG polyclonal antibody for TLR3 detection. Tested with WB, Direct ELISA in Human; Mouse; Rat.
Protein Function	Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response.
Subcellular Localization	Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome membrane. Early endosome.
Tissue Specificity	Expressed at high level in placenta and pancreas. Also detected in CD11c+ immature dendritic cells. Only expressed in dendritic cells and not in other leukocytes, including monocyte precursors. TLR3 is the TLR that is expressed most strongly in the brain, especially in astrocytes, glia, and neurons.
Contents	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na₂HPO₄, 0.05mg NaN₃.
Immunogen	E. coli-derived human TLR3 recombinant protein (Position: F502-D648).
Cross Reactivity	No cross reactivity with other proteins.
Storage	At -20?C; for one year. After r?Constitution, at 4?C; for one month. It?Can also be aliquotted and stored frozen at -20?C; for a longer time. Avoid repeated freezing and thawing.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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