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Anti-Bcl-2 Picoband Antibody

Anti-Bcl-2 Picoband Antibody

Item no.	ABC-ABO10009
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Lyophilized
Applications	WB, ELISA, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	BCL2, Apoptosis regulator Bcl-2
Available
Primary Accession	P10415
Application	WB, IHC-P, E
Clonality	Polyclonal
Gene ID	596
Reactivity	H, M, Rat
Calculated MW	26266
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Description	Rabbit IgG polyclonal antibody for Bcl-2 detection. Tested with WB, IHC-P, Direct ELISA in Human; Mouse; Rat.
Protein Function	Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).
Subcellular Localization	Mitochondrion outer membrane.
Tissue Specificity	Expressed in a variety of tissues.
Contents	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na₂HPO₄, 0.05mg NaN₃.
Immunogen	E. coli-derived human Bcl-2 recombinant protein (Position: Q118-E165).
Cross Reactivity	No cross reactivity with other proteins.
Storage	At -20?C; for one year. After r?Constitution, at 4?C; for one month. It?Can also be aliquotted and stored frozen at -20?C; for a longer time. Avoid repeated freezing and thawing.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 10/4/2024

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