Item no. |
A24235-500T |
Manufacturer |
Abclonal
|
Amount |
500 T |
Category |
|
Type |
Antibody Monoclonal |
Applications |
FC |
Specific against |
Human |
Isotype |
IgG |
Conjugate/Tag |
ABflo® 594. Ex:594nm. Em:619nm. |
Purity |
Affinity purification |
Sequence |
PTEIPTSALVKETLALLSTHRTLLIANETLRIPVPVHKNHQLCTEEIFQGIGTLESQTVQGGTVERLFKNLSLIKKYIDGQKKKCGEERRRVNQFLDYLQEFLGVMNTEWIIES |
NCBI |
IL-5 |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
IL5; EDF; IL-5; TRF; interleukin-5 |
Available |
|
Background |
This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. |
Route |
Recombinant protein |
Manufacturers Category |
Monoclonal Antibodies |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to aminoacids 20-134 of human IL5(NP_000870.1). |
Storage |
Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.03% proclin300, 0.2% BSA, pH7.3. |
Recommended Dilution |
FC(Intra), 5 μl per 10^6 cells in 100 μl volume |
Protein Size |
15kDa |
Manufacturers Research Area |
Cancer, Tumor immunology, Cell Biology & Developmental Biology, Growth factor, Immunology & Inflammation, Cytokines, Interleukins, Cell Intrinsic Innate Immunity Signaling Pathway, |
Gene Symbol |
IL-5 |
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