Item no. |
A23853-200T |
Manufacturer |
Abclonal
|
Amount |
200 T |
Category |
|
Type |
Antibody Monoclonal |
Applications |
FC |
Specific against |
Human |
Isotype |
IgG |
Conjugate/Tag |
ABflo® 647. Ex:656nm. Em:670nm. |
Purity |
Affinity purification |
Sequence |
ITQQDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKE |
NCBI |
TNFRSF1B |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
TNFRSF10B; CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9; TNF receptor superfamily member 10b |
Available |
|
Background |
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. |
Route |
Recombinant protein |
Manufacturers Category |
Monoclonal Antibodies |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 56-182 of human CD262/DR5/TRAILR2. |
Storage |
Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.03% proclin300, 0.2% BSA, pH7.3. |
Recommended Dilution |
FC, 5 μl per 10^6 cells in 100 μl volume |
Protein Size |
12kDa/45kDa/47kDa |
Manufacturers Research Area |
Cancer, Signal Transduction, Cell Biology & Developmental Biology, Apoptosis, Growth factor, TNF, Death Receptor Signaling Pathway, Immunology & Inflammation, CD markers, NF-kB Signaling Pathway, |
Gene Symbol |
TNFRSF10B |
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