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Anti-beta Catenin Rabbit pAb

Anti-beta Catenin Rabbit pAb

Item no.	PTM-6588
Manufacturer	PTM Biolabs
Amount	100 ul
Category	Antibodies Primary Antibodies
Type	Antibody Polyclonal
Format	Lyophilized powder
Applications	WB, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Catenin beta-1, CTNNB1, CTNNB, Beta-catenin
Shipping condition	Room temperature
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Category	Uncategorized
Manufacturer - Targets	beta Catenin
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Manufacturer - Research Area	Signal Transduction, Stem Cells, Cardiovascular Biology, Neuroscience, Cancer
Product description	Anti-beta Catenin Rabbit pAb
Purification Method	Protein A purified
Constituents	PBS, Glycerol, BSA
PTM	Unmodified
Clonality	Polyclonal
Stability	Stable for 12 months from date of receipt/reconstitution.
Background	β-Catenin is a key downstream effector in the Wnt signaling pathway, which is implicated in two major biological processes in vertebrates: early embryonic development and tumorigenesis. CK1 phosphorylates β-Catenin at Ser45. This phosphorylation event primes β-Catenin for subsequent phosphorylation by GSK-3β. GSK-3β destabilizes β-catenin by phosphorylating it at Ser33, Ser37, and Thr41. Mutations at these sites result in the stabilization of β-Catenin protein levels and have been found in many tumor cell lines.
Cellular Localization	Membrane, Cytoplasm

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/17/2025

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