Comparison

Anti-Phospho-IkB alpha (Ser32/36) Rabbit mAb

Item no. PTM-6401
Manufacturer PTM Biolabs
Amount 100 ul
Category
Type Antibody Monoclonal
Format Lyophilized powder
Applications WB, IHC-P
Clone JRMR-10764-13
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias NFKBIA, IKBA, MAD3, NFKBI
Shipping condition Room temperature
Available
Manufacturer - Type
Primary Antibodies
Manufacturer - Category
Uncategorized
Manufacturer - Targets
IkB alpha
Storage Conditions
Store at -20°C. Avoid freeze/thaw cycles.
Manufacturer - Research Area
Signal Transduction, Immunology, Cancer
Product description
Anti-Phospho-IKB alpha (Ser32/36) Rabbit mAb
Purification Method
Protein A purified
Constituents
PBS, Glycerol, BSA
PTM
Phospho
Modification Site
Ser32, Ser36
Clonality
Recombinant Monoclonal
Stability
Stable for 12 months from date of receipt/reconstitution.
Background
NF-kappa-B inhibitor alpha (IKB alpha) inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, IKB alpha becomes phosphorylated promoting itself ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Cellular Localization
Nucleus, cytoplasm

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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