Anti-Propionyl-Histone H3 (Lys14) Rabbit pAb

Histone & Histone Modification Antibodies

Store at -20°C. Avoid freeze/thaw cycles.

Epigenetics

Protein A purified

Propionyl

Polyclonal

Histones are subject to a variety of enzyme catalyzed modifications, including acetylation, methylation, phosphorylation, ubiquitylation, etc. Lysine propionylation (Kprop) is structurally similar to lysine acetylation, is a newly identified reversible modification controlling protein activity. Lysine propionylation is abundant in both prokaryotes and eukaryotes and has been found in wide ranges of proteins, including histones and non-histone substrates, such as p53. Similar to acetylation of histone H3 at Lys12, propionylation of histone H3 at Lys14 may play a vital role in the epigenetic modulation, including chromatin remodeling and transcriptional regulation.