Item no. |
ICH4015-1mg |
Manufacturer |
IchorBio
|
Amount |
1 mg |
Quantity options |
1 ea
1 mg
20 mg
5 mg
|
Category |
|
Type |
Biosimilars |
Specific against |
Human (Homo sapiens) |
Isotype |
IgG1 |
Purity |
>95% by SDS-PAGE and HPLC |
Formula |
Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free. |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Vascular endothelial growth factor |
Shipping condition |
Cool pack |
Available |
|
Manufacturer - Category |
Low endotoxin, Biosimilar, recombinant protein |
Manufacturer - Isotype |
Human IgG1 |
Manufacturer - Targets |
VEGF |
Manufacturer - Host |
Humanized |
Shipping Temperature |
Blue ice |
Storage Conditions |
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. |
Formulation |
Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free. |
Background |
Aflibercept biosimilar is a recombinant fusion protein consisting of portions of human VEGF receptors 1 and 2 extracellular domains fused to the Fc portion of human IgG1 formulated as an iso-osmotic solution for intravitreal administration. Aflibercept biosimilar is a dimeric glycoprotein with a protein molecular weight of 97 kilodaltons (kDa) and contains glycosylation, constituting an additional 15% of the total molecular mass, resulting in a total molecular weight of 115 kDa. Aflibercept biosimilar is produced in recombinant Chinese hamster ovary (CHO) cells. |
Concentration |
1.0 - 5.0 mg/ml |
Endotoxin |
≤ 1.0 EU/mg as determined by the LAL method |
Manufacturer - Specificity |
Detects human VEGF. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Aflibercept. |
Purification method |
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
Use |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
Isotype Control |
Bulk Human IgG1 Isotype Control (IB1) [ICH2254] |
Buffer |
ICH3001-100ml ICH3002-100ml ICH3003-100ml |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.