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Anti-Mouse PD-1 (RMP1-14) Recombinant Antibody

Anti-Mouse PD-1 (RMP1-14) Recombinant Antibody

Item no.	ICH1182-20mg
Manufacturer	IchorBio
Amount	20 mg
Quantity options	100 mg 10 mg 1 mg 20 mg 25 mg 50 mg 5 mg
Category	Antibodies Primary Antibodies
Type	Antibody
Applications	WB, FC, Blocking, FA
Clone	RMP1-14
Specific against	Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG2a
Purity	>95% by SDS-PAGE and HPLC
Formula	0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Programmed cell death protein 1, Pdcd1, CD279
Shipping condition	Cool pack
Available
Manufacturer - Applications	Western Blot, Blocking, Flow Cytometry, Functional Assays
Manufacturer - Category	Low Endotoxin, anti-mouse, monoclonal antibody
Manufacturer - Isotype	Mouse IgG2a
Manufacturer - Targets	PD-1
Shipping Temperature	Blue ice
Storage Conditions	Mouse anti-mouse PD-1 antibody (RMP1-14) is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -70oC.
Aggregation	Aggregation level ≤ 5%
Formulation	0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution	Subset of double negative thymocytes, activated T and B cells
Application Notes	Each investigator should determine their own optimal working dilution for specific applications.
Background	CD279, also known as programmed death-1 (PD-1) is a 50-55 kD immunoglobulin superfamily member. PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. This RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production.
Concentration	1.0 - 5.0 mg/ml
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity	Mouse anti-PD-1 antibody (RMP1-14) is a recombinant antibody where the original Rat IgG2a backbone of clone RMP1-14 has been changed to Mouse IgG1. This antibody recognizes an epitope on Mouse PD-1
Purification method	This monoclonal antibody was purified using Protein A
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Immunogen	Mouse PD-1 transfected BHK cells
Isotype Control	Mouse IgG1 Isotype Control for In Vivo - Low Endotoxin [HKSP] (ICH2247)
Buffer	ICH3001-100ml ICH3002-100ml ICH3003-100ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 mg

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Delivery expected until 2/7/2025

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