Exendin-4 Recombinant

Product Name: Exendin-4 Recombinant
Synonyms: Exenatide.
Description: Exendin-4 Recombinant is a novel 39-amino acids peptide having a molecular mass of 4186.7 Dalton, which shares 53%, sequence homology with GLP-17-36 amide and interacts with the same membrane receptor. The Exendin-4 is purified by proprietary chromatographic techniques.
Uniprot Accesion Number: P26349
Amino Acid Sequence:The sequence determined and was found to be His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser.
Source: Escherichia Coli.
Physical Appearance and Stability: Lyophilized Exendin Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution Exendin-4 should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Formulation and Purity: The Exendin-4 peptide was lyophilized after extensive dialyses against 20mM PBS and contains 4% mannitol. Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Application:
Solubility: It is recommended to reconstitute the lyophilized Exendin Recombinant in sterile 18MO-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity: 1. Regulates Glucose levels rapidly2. Reduces Insulin resistence 3. Reduces Glucagon4. Reduces HbA1c5. Stimulates beta cell growth which stimulates insulin production.
Shipping Format and Condition: Lyophilized powder at room temperature.
Usage Statement: Our products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.