Mouse Monoclonal Antibody to UCP3

Catalog Number: sAP-1338
Product Name: Mouse Monoclonal Antibody to UCP3
Target Molecle: UCP3
Aliases: SLC25A9
Species: Human;
MW: 34.2kDa
Enterez GeneID: 7352
General Information: Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression; this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene.;
Immunogen: Purified recombinant fragment of human UCP3 (AA: 1-113 and 217-312) expressed in E. Coli.
Clone: MM6B8C6;
Isotype: Mouse IgG2a
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage: Reconstitued with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; IHC: ; ICC: 1 to 200 - 1 to 1000; FCM:
References: 1.BMC Cancer. 2013 Mar 14; 13:115. ; 2.Oncol Rep. 2012 Dec; 28(6):2035-42. ;