Mouse Monoclonal Antibody to UCP2

Catalog Number: sAP-1295
Product Name: Mouse Monoclonal Antibody to UCP2
Target Molecle: UCP2
Aliases: UCPH; BMIQ4; SLC25A8
Species: Human;
MW: 33.2kDa
Enterez GeneID: 7351
General Information: Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'.;
Immunogen: Purified recombinant fragment of human UCP2 (AA: 1-309) expressed in E. Coli.
Clone: MM6C8B3;
Isotype: Mouse IgG1
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage: Reconstitued with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; IHC: ; ICC: ; FCM:
References: 1.Neurosci Lett. 2014 Jan 24; 559:39-43. ; 2.Biochem Biophys Res Commun. 2011 Nov 4; 414(4):712-8.;