Mouse Monoclonal Antibody to MCM2

Catalog Number: sAP-0639
Product Name: Mouse Monoclonal Antibody to MCM2
Target Molecle: MCM2
Aliases: BM28; CCNL1; CDCL1; cdc19; D3S3194; MITOTIN; KIAA0030; MGC10606
Species: Human
MW: 125kDa
Enterez GeneID: 4171
General Information: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.
Immunogen: Purified recombinant fragment of human MCM2 expressed in E. Coli. ;
Clone: MM1E7;
Isotype: Mouse IgG1
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Ascitic fluid containing 0.03% sodium azide. ;
Reconstitution and Storage: Reconstitued with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; IHC: 1 to 200 - 1 to 1000; ICC: 1 to 200 - 1 to 1000; FCM: 1 to 200 - 1 to 400
References: 1. Cancer Epidemiol Biomarkers Prev. 2009 May; 18(5):1651-8. ; 2. Biochemistry. 2009 Jun 9; 48(22):4720-7. ;