Mouse Monoclonal Antibody to PARP

Catalog Number: sAP-0369
Product Name: Mouse Monoclonal Antibody to PARP
Target Molecle: PARP
Aliases: PARP; PPOL; ADPRT; ADPRT1; PARP-1; pADPRT-1; PARP1
Species: Human
MW: 117kDa
Enterez GeneID: 142
General Information: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Immunogen: Synthetic peptide of human PARP, conjugated to KLH.
Clone: MM7A10;
Isotype: Mouse IgG1
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage: Reconstitued with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; FCM: 1 to 200 - 1 to 400
References: 1. Biochem J. 1992 Dec 1; 288 ( Pt 2):395-405. ; 2. Oncogene. 2000 Mar 16; 19(12):1509-18. ; 3. Nature. 2002 Mar 14; 416(6877):183-7. ; 4. Radiat Res. 2003 Apr; 159(4):439-52. ;