Goat anti-ROR1 Antibody

Goat anti-ROR1 Antibody
Principle Name: ROR1
Official Symbol: ROR1
All Name and Symbols: ROR1; receptor tyrosine kinase-like orphan receptor 1; MGC99659; NTRKR1; dJ537F10.1; neurotrophic tyrosine kinase receptor-related 1
Accession Number(s): NP_005003.2
Peptide Sequence: GNKSQKPYKIDSKQA, is from C-Terminus (near)
Human Gene ID(s): 4919
Non-Human GeneID(s): 26563 (mouse); 362550 (rat);
Important Comments: This antibody is expected to recognize isoform 1 (NP_005003.2) only.
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As: lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20C. Minimize freezing and thawing.
Applications: Pep ELISA, IHC
Tested Species: Human
Peptide ELISA: antibody detection limit dilution 1 to 16000.
Immunohistochemistry: In paraffin embedded Human Breast Cancer shows membranous staining in invasive Cancer tissue. Recommended concentration: 3-6ug/ml. Paraffin embedded Human Prostate and Liver. Recommended concentration: 3ug/ml.
Reference(s): Calin GA, Cimmino A, Fabbri M, Ferracin M, Wojcik SE, Shimizu M, Taccioli C, Zanesi N, Garzon R, Aqeilan RI, Alder H, Volinia S, Rassenti L, Liu X, Liu CG, Kipps TJ, Negrini M, Croce CM. MiR-15a and miR-16-1 cluster functions in human leukemia. Proc Natl Acad Sci U S A. 2008 Apr 1; 105(13):5166-71. Epub 2008 Mar 24..PMID: 18362358