Description |
Goat anti-ROR1 Antibody Principle Name: ROR1 Official Symbol: ROR1 All Name and Symbols: ROR1; receptor tyrosine kinase-like orphan receptor 1; MGC99659; NTRKR1; dJ537F10.1; neurotrophic tyrosine kinase receptor-related 1 Accession Number(s): NP_005003.2 Peptide Sequence: GNKSQKPYKIDSKQA, is from C-Terminus (near) Human Gene ID(s): 4919 Non-Human GeneID(s): 26563 (mouse); 362550 (rat); Important Comments: This antibody is expected to recognize isoform 1 (NP_005003.2) only. Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied As: lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing. Applications: Pep ELISA, IHC Tested Species: Human Peptide ELISA: antibody detection limit dilution 1 to 16000. Immunohistochemistry: In paraffin embedded Human Breast Cancer shows membranous staining in invasive Cancer tissue. Recommended concentration: 3-6ug/ml. Paraffin embedded Human Prostate and Liver. Recommended concentration: 3ug/ml. Reference(s): Calin GA, Cimmino A, Fabbri M, Ferracin M, Wojcik SE, Shimizu M, Taccioli C, Zanesi N, Garzon R, Aqeilan RI, Alder H, Volinia S, Rassenti L, Liu X, Liu CG, Kipps TJ, Negrini M, Croce CM. MiR-15a and miR-16-1 cluster functions in human leukemia. Proc Natl Acad Sci U S A. 2008 Apr 1; 105(13):5166-71. Epub 2008 Mar 24..PMID: 18362358 |