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(2S)-N-Fmoc-5-azido-pentanoic acid

(2S)-N-Fmoc-5-azido-pentanoic acid

Item no.	AS-65518-1
Manufacturer	AnaSpec
CASRN	1097192-04-5
Amount	1 g
Category	Peptides & Proteins Amino Acids
Type	Amino Acids
Specific against	other
Citations	1. Vallee, MRJ. et al. (2011). Staudinger-Phosphonite Reactions for the Chemoselective Transformation of Azido-Containing Peptides and Proteins. Org Lett 13, 5440.2. Staudinger, H. & Meyer, J. (1919). Uberneueorganische Phosphorverbindungen III. Phosphinmethylenederivative und Phosphinimine. Helvetica Chim Acta 2, 635.3. Oh, K-I. et al. (2008). ß-Azidoalanine as an IR Probe: Application to Amyloid Aß (16-22) Aggregation. J Phys Chem B 112, 10352.
ECLASS 10.1	32160406
ECLASS 11.0	32160406
UNSPSC	12352209
Alias	1097192-04-5
Similar products	1097192-04-5
Available
Description	This unusual amino acid is used in Solid Phase Peptide Synthesis (SPPS) for the synthesis of modifiable side-chain peptides and proteins.1 The side-chain azido (N3) group is stable in trifluoroacetic acid (TFA) and piperidine (Pip), two reagents commonly used in SPPS. The azido group can be readily converted to an amine on the solid phase or in solution via Staudinger reduction.2 In addition, incorporation of azidohomoalanine into proteins has shown promise as an effective IR probe of local electrostatic environments in proteins.3
MF	C20H20N4O4
MW	380, 4
Product Group	RE1C1C
Shipping	RT
Storage	-20C

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Amount: 1 g

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Delivery expected until 8/16/2024