Comparison

SensoLyte® 520 Acetylcholinesterase Assay Kit Fluorimetric - 1 kit

Item no. AS-72242
Manufacturer AnaSpec
Amount 1 kit
Category
Type Assay-Kit
Specific against other
Host CHO cells, Mammalian cells
Conjugate/Tag Unconjugated
Dry ice Yes
ECLASS 10.1 32161090
ECLASS 11.0 32161090
UNSPSC 41116126
Shipping condition Dry ice
Available
Manufacturer - Applications
FRET; Protease activity
Manufacturer - Category
Assay Kits
Manufacturer - Targets
Acetylcholinesterase
Manufacturer - Host
Mammalian Cells, CHO Cells
Shipping Temperature
Dry Ice
Storage Conditions
Store component B at -80°C. Store all other components at -20°C. Protect component A from light and moisture.
Description
The SensoLyte 520 Acetylcholinesterase Assay Kit is a homogeneous assay that can be used to detect the activity of enzyme and for screening of AChE inhibitors. Active AChE generates fluorescence that can be monitored at excitation/emission=490/520 nm. The long wavelength fluorescence of the substrate in this kit minimizes interference from autofluorescence of components in biological samples and test compounds, resulting in higher sensitivity. - Optimized to detect human AChE - Detect as low as 8 pg/ml of active AChE - 200 assays in 96-well format - Entire process can be completed in 1 hour Acetylcholinesterase (AChE) is a fast acting serine hydrolase that belongs to the carboxylesterase enzyme family. It hydrolyses acetylcholine into choline and acetic acid and is found in the synaptic cleft. It can be detected in many mammals and non-mammalian species. Alzheimer and myasthenia gravis diseases are characterized by reduced acetylcholine. Thus, drugs that inhibit AChE were developed to reduce disease symptoms. AChE can be inhibited by many natural substances such as alkaloids and synthetic chemicals such as organophosphorous compounds that are frequently used as pesticides. Recently, it was demonstrated that natural compounds have variable inhibitory effect on AChE depending on the species. *For Research Use Only*
Product Group
NA1ZZZ
Research Area
Neuroscience / 0
Absorbtion (nm)
490
Emission (nm)
520
GTIN
5400535130015
Detection Method
Fluorescent
Detection Limit
8 pg/ml
Usage
Research use
UNSPSC
41105331

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 kit
Available: In stock
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