« Back
Home /
Transforming Growth Factor-alpha, TGF-alpha, Human, Recombinant

Transforming Growth Factor-alpha, TGF-alpha, Human, Recombinant

Item no.	ARP-28-10309-100
Manufacturer	American Research Products
Amount	100 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Description	TGF-alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-alpha induces transformation anchorage independence in cultured cells. Human, murine and rat TGF-alpha are cross-species reactive. Recombinant human TGF-alpha is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.
Storage	Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms	Sacroma growth factor, TGF-type I, ETGF
Purity	0, 98
Source	E. Coli
Interest Fields	Angiogenesis/Cardiovascular, Cancer, Inflammation, Wound Healing
Amino Acid Sequence	VVSHFNDCPD SHTQFCFHGT CRFLVQEDKP ACVCHSGYVG ARCEHADLLA
Endotoxin Level	Endotoxin level is <, 0.1 ng/ug of protein (<, 1EU/ug).
Biological Activity	The ED 50 as determined by the dose-dependent stimulation of thymidine uptake by BALB/c 3T3 cells is a‰¤ 0.2 ng/ml, corresponding to a specific activity of a‰¥ 5 x 10^6 units/mg.
Protein Content	Verified by UV Spectroscopy and/or SDS-PAGE gel.
Authenticity	Verified by N-terminal and Mass Spectrometry analyses (when applicable).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100 ug

available

Delivery expected until 9/20/2024