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Macrophage-Derived Chemokine, MDC (69 a.a.) (CCL22), Human, Recombinant

Macrophage-Derived Chemokine, MDC (69 a.a.) (CCL22), Human, Recombinant

Item no.	ARP-28-10217-20
Manufacturer	American Research Products
Amount	20 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Description	MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells and exerts HIV suppressive activity. The 67 amino acid form of MDC displays reduced chemoattractant activity but retains HIV suppressive activity. Recombinant human MDC is an 8.1 kDa protein containing 69 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Storage	Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms	CCL22, STCP-1, ABCD-1
Purity	0, 98
Source	E. Coli
Interest Fields	AIDS/HIV, Chemotaxis, Immune System, Wound Healing
Amino Acid Sequence	GPYGANMEDS VCCRDYVRYR LPLRVVKHFY WTSDSCPRPG VVLLTFRDKE ICADPRVPWV KMILNKLSQ
Endotoxin Level	Endotoxin level is <, 0.1 ng/ug of protein (<, 1EU/ug).
Biological Activity	Determined by its ability to chemoattract human T cells using a concentration range of 10.0-100.0 ng/ml.
Protein Content	Verified by UV Spectroscopy and/or SDS-PAGE gel.
Authenticity	Verified by N-terminal and Mass Spectrometry analyses (when applicable).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

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Delivery expected until 9/20/2024

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