Manufacturer |
American Research Products
|
Category |
|
Type |
Proteins Recombinant |
Specific against |
other |
Amount |
1 mg |
Item no. |
ARP-28-10210-1 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Available |
|
Description |
Maspin (mammary serine protease inhibitor) is a non-inhibitory serpin that is expressed predominantly in normal mammary epithelial cells but at significantly reduced levels or absent in most breast carcinomas. It has the ability to block the growth, invasiveness, and metastatic potential of breast and lung tumors. This anti-tumor activity is achieved, in part, by the ability of Maspin to inhibit angiogenesis and to preferentially promote apoptosis of tumor cells. Recombinant human Maspin is a 42.1 kDa non-glycosylated protein containing 375 amino acid residues. |
Storage |
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Synonyms |
SerpinB5, Protease inhibitor 5 |
Purity |
0, 97 |
Source |
E. Coli |
Interest Fields |
Angiogenesis/Cardiovascular, Apoptosis, Cancer, Wound Healing |
Amino Acid Sequence |
MDALQLANSA FAVDLFKQLC EKEPLGNVLF SPICLSTSLS LAQVGAKGDT ANEIGQVLHF ENVKDIPFGF QTVTSDVNKL SSFYSLKLIK RLYVDKSLNL STEFISSTKR PYAKELETVD FKDKLEETKG QINNSIKDLT DGHFENILAD NSVNDQTKIL VVNAAYFVGK WMKKFPESET KECPFRLNKT DTKPVQMMNM EATFCMGNID SINCKIIELP FQNKHLSMFI LLPKDVEDES TGLEKIEKQL NSESLSQWTN PSTMANAKVK LSIPKFKVEK MIDPKACLEN LGLKHIFSED TSDFSGMSET KGVALSNVIH KVCLEITEDG GDSIEVPGAR ILQHKDELNA DHPFIYIIRH NKTRNIIFFG KFCSP |
Endotoxin Level |
Endotoxin level is <, 0.1 ng/ug of protein (<, 1EU/ug). |
Protein Content |
Verified by UV Spectroscopy and/or SDS-PAGE gel. |
Authenticity |
Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.