Item no. |
ARP-28-10158-2 |
Manufacturer |
American Research Products
|
Amount |
2 ug |
Category |
|
Type |
Proteins Recombinant |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Available |
|
Description |
G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant human G-CSF is an 18.7 kDa protein consisting of 174 amino acid residues. |
Storage |
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Synonyms |
CSF-3, MGI-1G, GM-CSF beta, pluripoietin |
Purity |
0, 98 |
Source |
E. Coli |
Interest Fields |
AIDS/HIV, Angiogenesis/Cardiovascular, Cancer, Diabetes / Weight Regulation, Inflammation, Stem Cells &, Differentiation |
Amino Acid Sequence |
TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLGIPW APLSSCPSQA LQLAGCLSQL HSGLFLYQGL LQALEGISPE LG PTLDTL QLDVADFATT IWQQMEELGM APALQPTQGA MPAFASAFQR RAGG VLVA SHLQSFLEVS YRVLRHLAQP |
Endotoxin Level |
Endotoxin level is <, 0.1 ng/ug of protein (<, 1EU/ug). |
Biological Activity |
The ED 50 as determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is a‰¤ 0.1 ng/ml, corresponding to a specific activity of a‰¥ 1 x 10^7 units/mg. |
Protein Content |
Verified by UV Spectroscopy and/or SDS-PAGE gel. |
Authenticity |
Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.