Manufacturer |
American Research Products
|
Category |
|
Type |
Proteins Recombinant |
Specific against |
other |
Amount |
100 ug |
Item no. |
ARP-11-IL-2MHT-100 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Available |
|
Description |
Interleukin-2 (IL-2), also known as T cell growth factor (TCGF), is an immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant mouse IL-2 protein was expressed in E.coli and purified by using conventional chromatography techniques. |
Form |
Liquid. In Phosphate Buffered Saline (pH7.4) containing 20% glycerol, 0.1M NaCl |
Storage |
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Synonyms |
IL-2, T-cell growth factor, TCGF, Il-2, Interleukin-2, il2, interleukin 2, il 2 |
Concentration |
0.5 mg/ml (determined by Bradford assay) |
NCBI |
NP_032392 |
References |
- Morgan DA., et al. (1976). Science. 193, 1007-8.
- Watson J., et al. (1980). Immunol Rev. 51, 257-78.
- Taniguchi T., et al. (1983). Nature. 302, 305-10.
|
Antigen Recognized in Species |
Mouse |
Purity |
>, 90% by SDS - PAGE |
Molecular Weight |
19.5 kDa (170 aa), confirmed by MALDI-TOF. |
Amino Acid Sequence |
MGSSHHHHHH SSGLVPRGSH MAPTSSSTSS STAEAQQQQQ QQQQQQQHLE QLLMDLQELL SRMENYRNLK LPRMLTFKFY LPKQATELKD LQCLEDELGP LRHVLDLTQS KSFQLEDAEN FISNIRVTVV KLKGSDNTFE CQFDDESATV VDFLRRWIAF CQSVISTSPQ |
Gene Category |
Hormones &, Cytokines |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.