Item no. |
ARP-01-P2617-100 |
Manufacturer |
American Research Products
|
Amount |
100 ug |
Category |
|
Type |
Proteins Recombinant |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Available |
|
Description |
IRF5 is a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism Recombinant human IRF5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Form |
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT |
Storage |
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Synonyms |
interferon regulatory factor 5 isoform b, SLEB10 |
Concentration |
0.25 mg/ml (determined by Bradford assay) |
NCBI |
NP_116032.1 |
References |
- Barnes B.J., et al (2001). J. Biol. Chem. 276:23382-23390
- Schoenemeyer A., et al (2005). J. Biol. Chem. 280:17005-17012
|
Antigen Recognized in Species |
Human |
Purity |
>, 85 % by SDS - PAGE |
Molecular Weight |
10.7 kDa (101aa) confirmed by MALDI-TOF |
Amino Acid Sequence |
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSPPTL QPPTLQPPVV LGPPAPDPSP LAPPPGNPAG FRELLSEVLE PGPLPASLPP AGEQLLPDLL I |
Gene Category |
Epigenomics (Transcription &, Translation) |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.