Item no. |
ARP-01-P2560-250 |
Manufacturer |
American Research Products
|
Amount |
250 ug |
Category |
|
Type |
Proteins Recombinant |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Available |
|
Description |
Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Recombinant human EPHX1 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Form |
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea |
Storage |
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Synonyms |
Epoxide hydrolase 1, microsomal (xenobiotic), Epoxide hydrolase 1, microsomal (xenobiotic), MEH, EPHX, EPOX |
Concentration |
0.25 mg/ml (determined by Bradford assay) |
NCBI |
NP_000111 |
References |
- Nguyen HL, et al. RNA, (2013). PMID 23564882.
- Wang S, et al. Tumour Biol, (2013). PMID 23378225.
|
Antigen Recognized in Species |
Human |
Purity |
>, 90 % by SDS - PAGE |
Molecular Weight |
52.2 kDa (451aa) |
Amino Acid Sequence |
MASMTGGQQM GRGSHMRDKE ETLPLEDGWW GPGTRSAARE DDSIRPFKVE TSDEEIHDLH QRIDKFRFTP PLEDSCFHYG FNSNYLKKVI SYWRNEFDWK KQVEILNRYP HFKTKIEGLD IHFIHVKPPQ LPAGHTPKPL LMVHGWPGSF YEFYKIIPLL TDPKNHGLSD EHVFEVICPS IPGYGFSEAS SKKGFNSVAT ARIFYKLMLR LGFQEFYIQG GDWGSLICTN MAQLVPSHVK GLHLNMALVL SNFSTLTLLL GQRFGRFLGL TERDVELLYP VKEKVFYSLM RESGYMHIQC TKPDTVGSAL NDSPVGLAAY ILEKFSTWTN TEFRYLEDGG LERKFSLDDL LTNVMLYWTT GTIISSQRFY KENLGQGWMT QKHERMKVYV PTGFSAFPFE LLHTPEKWVR FKYPKLISYS YMVRGGHFAA FEEPELLAQD IRKFLSVLER Q |
Gene Category |
Metabolism |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.