Item no. |
ARP-01-P1886-10 |
Manufacturer |
American Research Products
|
Amount |
10 ug |
Category |
|
Type |
Proteins Recombinant |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Available |
|
Description |
KLRG1 belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. Cell surface expression of KLRG1 is up-regulated by expression of MHC class I molecules. Recombinant human KLRG1 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Form |
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol |
Storage |
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Synonyms |
Killer cell lectin-like receptor subfamily G member 1, 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE |
Concentration |
0.5 mg/ml (determined by Bradford assay) |
NCBI |
NP_005801 |
References |
- Schwartzkopff S, Grundemann C, et al. (2007). J Immunol. 179(2):1022-9.
- Ibegbu CC, Xu YX, et al. (2005). J Immunol. 174(10):6088-94.
|
Antigen Recognized in Species |
Human |
Purity |
>, 85% by SDS - PAGE |
Molecular Weight |
17kDa (153aa) |
Amino Acid Sequence |
MGSSHHHHHH SSGLVPRGSH MGSLCQGSNY STCASCPSCP DRWMKYGNHC YYFSVEEKDW NSSLEFCLAR DSHLLVITDN QEMSLLQVFL SEAFCWIGLR NNSGWRWEDG SPLNFSRISS NSFVQTCGAI NKNGLQASSC EVPLHWVCKK VRL |
Gene Category |
Immunology |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.