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SMNDC1, 1-238aa, Human, His tag, E.coli

SMNDC1, 1-238aa, Human, His tag, E.coli

Item no.	ARP-01-P0807-250
Manufacturer	American Research Products
Amount	250 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Description	SMNDC1 (survival motor neuron domain containing 1) is an essential splicing factor required for spliceosome assembly that belongs to the SMN family. It contains one Tudor domain with significant similarity to SMN (Survival Motor Neuron) and is expressed in skeletal muscle, pancreas and heart, localizing to Cajal bodies and nuclear speckles. Mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. Recombinant human SMNDC1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Form	Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 1mM DTT, 100mM NaCl
Storage	Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms	Survival of motor neuron-related-splicing factor 30, Survival of motor neuron-related-splicing factor 30
Concentration	0.5mg/ml (determined by Bradford assay)
NCBI	NP_005862
References	Meister G., et al. (2001) EMBO J. 20:2304-2314 Talbot K., et al. (1998) Hum. Mol. Genet. 7:2149-2156
Antigen Recognized in Species	Human
Purity	>, 90% by SDS - PAGE
Molecular Weight	28.9kDa (258aa), confirmed by MALDI-TOF
Amino Acid Sequence	MGSSHHHHHH SSGLVPRGSH MSEDLAKQLA SYKAQLQQVE AALSGNGENE DLLKLKKDLQ EVIELTKDLL STQPSETLAS SDSFASTQPT HSWKVGDKCM AVWSEDGQCY EAEIEEIDEE NGTAAITFAG YGNAEVTPLL NLKPVEEGRK AKEDSGNKPM SKKEMIAQQR EYKKKKALKK AQRIKELEQE REDQKVKWQQ FNNRAYSKNK KGQVKRSIFA SPESVTGKVG VGTCGIADKP MTQYQDTSKY NVRHLMPQ
Gene Category	Apoptosis

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Amount: 250 ug

available

Delivery expected until 8/23/2024