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PNPO, 57-261aa, Human, His tag, E.coli

PNPO, 57-261aa, Human, His tag, E.coli

Manufacturer	American Research Products
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Amount	100 ug
Item no.	ARP-01-2390-O-100
eClass 6.1	34160400
eClass 9.0	42020190
Available
Description	PNPO, also known as pyridoxine-5'-phosphate oxidase, is the rate-limiting enzyme in vitamin B6 synthesis. Vitamin B6, or pyridoxal 5-prime-phosphate (PLP), is critical for normal cellular function, and some cancer cells have notable differences in vitamin B6 metabolism compared to their normal counterparts. Recombinant human PNPO protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography
Form	Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.1M NaCl, 0.1mM PMSF
Storage	Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms	Pyridoxine-5'-phosphate oxidase , FLJ10535, PDXPO
Concentration	0.5 mg/ml (determined by Bradford assay)
NCBI	NP_060599
References	Ngo EO., et al. (1998), Biochemistry., 37(21):7741-8 Kang JH., et al. (2004). Eur J Biochem., 271(12):2452-61
Antigen Recognized in Species	Human
Purity	>, 90% by SDS - PAGE
Molecular Weight	25.9 kDa (226aa) confirmed by MALDI-TOF (molecular weight on SDS-PAGE will appear higher)
Amino Acid Sequence	MGSSHHHHHH SSGLVPRGSH MDPVKQFAAW FEEAVQCPDI GEANAMCLAT CTRDGKPSAR MLLLKGFGKD GFRFFTNFES RKGKELDSNP FASLVFYWEP LNRQVRVEGP VKKLPEEEAE CYFHSRPKSS QIGAVVSHQS SVIPDREYLR KKNEELEQLY QDQEVPKPKS WGGYVLYPQV MEFWQGQTNR LHDRIVFRRG LPTGDSPLGP MTHRGEEDWL YERLAP
Gene Category	Metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 8/23/2024

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