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Alpha-1-antichymotrypsin, 24-423 aa, Human, His-tag, E.coli

Alpha-1-antichymotrypsin, 24-423 aa, Human, His-tag, E.coli

Item no.	ARP-01-2190-100
Manufacturer	American Research Products
Amount	100 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Description	Alpha-1-antichymotrypsin is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. Recombinant alpha-1-antichymotrypsin protein was expressed in E.coli and purified by using conventional chromatography techniques.
Form	Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT.
Storage	Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms	AACT, ACT, GIG24, GIG25, SERPINA3, Serpin peptidase inhibitor, clade A, member 3 Cell growth inhibiting gene 24/25 protein, Growth inhibiting protein 24, Antichymotrypsin, Growth inhibiting protein 25, MGC88254, Serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase, antitrypsin) member 3, Serine (or cysteine) proteinase inhibitor clade A member 3, Serine proteinase inhibitor clade A member 3, Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3.
Concentration	1 mg/ml (determined by Bradford assay)
NCBI	NP_001076
References	Kamboh MI., et al. (2006) Neurobiol Aging. 27(10):1435-9. Tachikawa H., et al. (2001) J Hum Genet. 46(1):45-7.
Antigen Recognized in Species	Human
Purity	>, 95% by SDS-PAGE
Molecular Weight	47.6 kDa (421aa), confirmed by MALDI-TOF.
Amino Acid Sequence	MGSSHHHHHH SSGLVPRGSH MHPNSPLDEE NLTQENQDRG THVDLGLASA NVDFAFSLYK QLVLKAPDKN VIFSPLSIST ALAFLSLGAH NTTLTEILKG LKFNLTETSE AEIHQSFQHL LRTLNQSSDE LQLSMGNAMF VKEQLSLLDR FTEDAKRLYG SEAFATDFQD SAAAKKLIND YVKNGTRGKI TDLIKDLDSQ TMMVLVNYIF FKAKWEMPFD PQDTHQSRFY LSKKKWVMVP MMSLHHLTIP YFRDEELSCT VVELKYTGNA SALFILPDQD KMEEVEAMLL PETLKRWRDS LEFREIGELY LPKFSISRDY NLNDILLQLG IEEAFTSKAD LSGITGARNL AVSQVVHKAV LDVFEEGTEA SAATAVKITL LSALVETRTI VRFNRPFLMI IVPTDTQNIF FMSKVTNPKQ A
Gene Category	Proteases &, Inhibitors

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 10/25/2024

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