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OAS1, 1-364 aa, Human, His-tagged, Recombinant, E.coli

OAS1, 1-364 aa, Human, His-tagged, Recombinant, E.coli

Item no.	ARP-01-2160-1-20
Manufacturer	American Research Products
Amount	20 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Description	OAS1 is an enzyme included in the 2', 5'-oligoadenylate synthase family. This enzyme is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2', 5'-oligoadenylates(2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. OAS1 may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. Recombinant OAS1 protein was expressed in E.coli and purified by using conventional chromatography techniques.
Form	Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol and 1mM DTT.
Storage	Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms	IFI-4, OIAS, OIASI, 2', 5'-oligoadenylate synthetase 1, isoform2 (2 5')oligo(A) synthetase 1, 2' 5' oligo A synthetase 1, 2 5 Oligoadenylate Synthetase 1, 2 5A synthetase 1, 2' 5' oligoadenylate synthetase 1, 2' 5' oligoisoadenylate synthetase 1, 2'5' oligoadenylate synthetase 1, 2'5' oligoisoadenylate synthetase 1, p46/p42 OAS, 2'5' oligo A synthetase 1, E18/E16, IFI 4, IFI4, OAS 1,
Concentration	1 mg/ml (determined by Bradford assay)
NCBI	NP_002525
References	Rios JJ., et al. (2007) BMC Genomics. 8:313. Tessier MC., et al. (2006) J Med Genet. 43(2):129-32.
Antigen Recognized in Species	Human
Purity	>, 95% by SDS-PAGE
Molecular Weight	43.9 kDa (384aa), confirmed by MALDI-TOF.
Amino Acid Sequence	MGSSHHHHHH SSGLVPRGSH MMDLRNTPAK SLDKFIEDYL LPDTCFRMQI NHAIDIICGF LKERCFRGSS YPVCVSKVVK GGSSGKGTTL RGRSDADLVV FLSPLTTFQD QLNRRGEFIQ EIRRQLEACQ RERAFSVKFE VQAPRWGNPR ALSFVLSSLQ LGEGVEFDVL PAFDALGQLT GSYKPNPQIY VKLIEECTDL QKEGEFSTCF TELQRDFLKQ RPTKLKSLIR LVKHWYQNCK KKLGKLPPQY ALELLTVYAW ERGSMKTHFN TAQGFRTVLE LVINYQQLCI YWTKYYDFKN PIIEKYLRRQ LTKPRPVILD PADPTGNLGG GDPKGWRQLA QEAEAWLNYP CFKNWDGSPV SSWILLVRPP ASSLPFIPAP LHEA
Gene Category	Enzymes
Endotoxin Level	<, 1.0 EU per 1 microgram of protein (determined by LAL method)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

available

Delivery expected until 8/23/2024