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CERT, 347-598aa, Human, His tag, E.coli

CERT, 347-598aa, Human, His tag, E.coli

Item no.	ARP-01-1846-0.5
Manufacturer	American Research Products
Amount	0.5 mg
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Description	CERT is a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Recombinant human CERT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Form	Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl
Storage	Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms	COL4A3BP, CERTL, GPBP, STARD11, Collagen, type IV, alpha 3 binding protein Alpha 3 type IV collagen binding protein, Ceramide transporter, CERT, Cert protein, Collagen type IV alpha 3 (Goodpasture antigen) binding protein, Collagen type IV alpha 3 binding protein, FLJ20597, Goodpasture antigen binding protein, Lipid transfer protein CERTL, Procollagen type IV alpha 3 (Goodpasture antigen) binding protein, StAR related lipid transfer protein 11, StARD 11, START domain containing 11, START domain containing protein 11,
Concentration	0.5 mg/ml (determined by Bradford assay)
NCBI	NP_112729
References	Turner N., et al. (1992) J Clin Invest 89(2):592-601.
Antigen Recognized in Species	Human
Purity	>, 95% by SDS - PAGE
Molecular Weight	33.1 kDa (290aa) confirmed by MALDI-TOF
Amino Acid Sequence	MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWAGSMLH WPTSLPSGDA FSSVGTHRFV QKVEEMVQNH MTYSLQDVGG DANWQLVVEE GEMKVYRREV EENGIVLDPL KATHAVKGVT GHEVCNYFWN VDVRNDWETT IENFHVVETL ADNAIIIYQT HKRVWPASQR DVLYLSVIRK IPALTENDPE TWIVCNFSVD HDSAPLNNRC VRAKINVAMI CQTLVSPPEG NQEISRDNIL CKITYVANVN PGGWAPASVL RAVAKREYPK FLKRFTSYVQ EKTAGKPILF
Gene Category	Immunology

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.5 mg

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Delivery expected until 10/25/2024

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