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CDK2AP1, 1-115aa, Human, His tag, E. coli

CDK2AP1, 1-115aa, Human, His tag, E. coli

Item no.	ARP-01-1783-1-0.5
Manufacturer	American Research Products
Amount	0.5 mg
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Description	CDK2AP1 is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. Also, interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes. Recombinant CDK2AP1 protein was expressed in E.coli and purified by using conventional chromatography techniques.
Form	Liquid. 20mM Tris-HCl buffer (pH8.0) containing 50% glycerol, 2mM DTT
Storage	Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms	CDKAP1, DOC1, CDKA1, Cyclin-dependent kinase 2 associated protein 1 CDK2 A1, CDK2 associated protein 1, CDK2AP1, Cyclin dependent kinase 2 associated protein 1 Deleted in oral cancer 1, DOC 1, DOC 1 related protein, DOC 1R, DOC1R, Putative oral cancer suppressor.
Concentration	0.25 mg/ml (determined by Bradford assay)
NCBI	NP_004633
References	Tsuji T., et al. (1998) J Biol Chem. 273(12):6704-9. Hu MG., et al. (2004) Cancer Res. 64(2):490-9.
Antigen Recognized in Species	Human
Purity	>, 95% by SDS - PAGE
Molecular Weight	16.6kDa (152aa), confirmed by MALDI-TOF.
Amino Acid Sequence	MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMSY KPNLAAHMPA AALNAAGSVH SPSTSMATSS QYRQLLSDYG PPSLGYTQGT GNSQVPQSKY AELLAIIEEL GKEIRPTYAG SKSAMERLKR GIIHARGLVR ECLAETERNA RS
Gene Category	Cell Cycle

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Amount: 0.5 mg

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Delivery expected until 9/20/2024

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