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Anti-Endothelial Cell Specific Molecule 1 (ESM1)

Anti-Endothelial Cell Specific Molecule 1 (ESM1)

Item no.	ARP-20-4586
Manufacturer	American Research Products
Amount	50 ug
Category	Antibodies Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC, ICC, ELISA
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	Endothelial cell-specific molecule 1 is encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. The cDNA sequence contains an open reading frame of 552 nucleotides. The deduced 184-amino acid protein is cysteine rich with an N-terminal hydrophobic signal sequence. Expression of ESM1 was tested by Northern blot analysis and RT-PCR and was found to be constitutive in a HUVEC cell line, but not in any other cell line tested. Constitutive ESM1 expression in human tissue is restricted to the lung. Immunoblotting and immunoprecipitation identified a 20-kD protein.
Form	Liquid
Working Dilution	Western blotting: 1:100-400, Immunocytochemistry in formalin fixed cells: 1:100-500, Immunohistochemistry in formalin fixed frozen section: 1:100-500, Immunohistochemistry in paraffin section: 1:50-417
Storage	2-8C for immediate use, or at -20C (aliquot)
Synonyms	Endocan
Concentration	0.2mg/ml
Antigen Recognized in Species	Rat
Purification	Affinity chromatography

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Amount: 50 ug

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Delivery expected until 8/23/2024