Item no. |
ARP-10-P2069 |
Manufacturer |
American Research Products
|
Amount |
100 ug |
Category |
|
Type |
Antibody Polyclonal |
Specific against |
other |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Available |
|
Description |
Rabbit IgG polyclonal antibody for Disintegrin and metalloproteinase domain-containing protein 2(ADAM2) detection. Tested with WB in Human. |
Background |
ADAM2 (A Disintegrin and Metalloproteinase Domain 2) , also known as FTNB or PH30, is an enzyme that in humans is encoded by the ADAM2 gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. Burkin et al. (1997) used fluorescence in situ hybridization to map the FTNB gene to 8p11.2. |
Immunogen |
A synthetic peptide corresponding to a sequence at the C-terminal of human ADAM2. |
Form |
Lyophilized |
Specificity |
Human. No cross reactivity with other proteins. |
Storage |
2-8C. For long term -20C after reconstitution. |
Synonyms |
FTNB, CT15, PH-30b, PH30, fertilin beta, cancer/testis antigen 15 |
References |
- 1. Gupta SK, Alves K, Palladino LO, Mark GE, Hollis GF (Aug 1996). Molecular cloning of the human fertilin beta subunit. Biochem Biophys Res Commun 224 (2): 318-26.
- 2. Burkin, H. R., Burkin, D. J., Davey, P. M., Griffin, D. K., Affara, N. A. Mapping, sequence, and expression analysis of the human fertilin beta gene (FTNB). Genomics 40: 190-192, 1997.
|
Reconstitution |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Purification |
Immunogen affinity purified. |
Contents |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.