Comparison

Anti-Serotonin

Item no. ARP-03-11160
Manufacturer American Research Products
Amount 100 ul
Category
Type Antibody Polyclonal
Applications IF, ELISA
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Available
Background
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.
Immunogen
Serotonin/Ovalbumin
Form
Serum containing 0.1% sodium azide
Specificity
The polyclonal antibody to serotonin can be used to differentiate tumors of serotoninergic origin. The antigen localization is cytoplasmic.
Working Dilution
1:25 for immunohistochemistry (optimal dilution should be tested by serial dilution)
Storage
2-8C for immediate use, or at -20C (aliquot)
Synonyms
HTT, 5HTT, OCD1, SERT, 5-HTT, SERT1, hSERT, 5-HTTLPR
References
Arends JW et al. (1986) J Pathology 149: 97-102
Antigen Recognized in Species
Most species, incl. Human, Mouse, Rat
Positive Control
Duodenum/Formalin-fixed paraffin sections of human intestine

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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