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JNJ-28312141

JNJ-28312141

Item no.	A12687-5
Manufacturer	Adooq
Amount	5mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	CAS-No: 885692-52-4
Similar products	JNJ-28312141
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Short Description	JNJ-28312141 is an orally active CSF1R inhibitor (Colony-stimulating factor-1 receptor, CRF1R) and also a FLT3 inhibitor. CSF1R is expressed by many tumors and is a growth factor for macrophages and mediates osteoclast differentiation. JNJ-28312141 represents a new agent with potential therapeutic activity in acute myeloid leukemia and in settings where CSF-1-dependent macrophages and osteoclasts contribute to tumor growth and skeletal events.
Cas No	885692-52-4
Synonyms	JNJ 28312141, JNJ28312141
Formula	C26H32N6O2
Solubilty	DMSO
Purity	>98%
Chemical Name	4-cyano-N-(5-(1-(2-(dimethylamino)acetyl)piperidin-4-yl)-2', 3', 4', 5'-tetrahydro-[1, 1'-biphenyl]-2-yl)-1H-imidazole-2-carboxamide
M. Wt.	460, 57
SMILES	CN(C)CC(=O)N1CCC(CC1)C2=CC(=C(C=C2)NC(=O)C3=NC=C(N3)C#N)C4=CCCCC4
Storage	2 years at -20C

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5mg

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