« Back
Home /
Quarfloxin (CX-3543)

Quarfloxin (CX-3543)

Item no.	A12380-25
Manufacturer	Adooq
Amount	25mg
Category	Food Safety Antibiotics Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	CAS-No: 865311-47-3
Similar products	Quarfloxin (CX-3543)
Available
Short Description	Quarfloxin (CX-3543) is a fluoroquinolone derivative with antineoplastic activity. Quarfloxin disrupts the interaction between the nucleolin protein and a G-quadruplex DNA structure in the ribosomal DNA (rDNA) template, a critical interaction for rRNA biogenesis that is overexpressed in cancer cells; disruption of this G-quadruplex DNA:protein interaction in aberrant rRNA biogenesis may result in the inhibition of ribosome synthesis and tumor cell apoptosis.
Cas No	865311-47-3
Synonyms	CX 3543; Quarfloxacin; CX3543; CX-3543
Formula	C35H33FN6O3
Solubilty	DMSO
Purity	>98%
Chemical Name	5-fluoro-N-(2-((S)-1-methylpyrrolidin-2-yl)ethyl)-3-oxo-6-((R)-3-(pyrazin-2-yl)pyrrolidin-1-yl)-3H-benzo[b]pyrido[3, 2, 1-kl]phenoxazine-2-carboxamide.
M. Wt.	604, 67
SMILES	CN1CCC[C@ H]1CCNC(=O)C2=CN3C4=CC5=CC=CC=C5C=C4OC6=C3C(=CC(=C6N7CCC(C7)C8=NC=CN=C8)F)C2=O
Storage	2 years at -20C

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 25mg

available

Delivery expected until 8/30/2024

Express Delivery: Save 14 days

Compare

Add to wishlist

Recommend by mail