Short Description |
Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis. |
Chemical Name |
2-((2S, 5R, 8S, 11S)-5-benzyl-11-(3-((diaminomethylene)amino)propyl)-8-isopropyl-7-methyl-3, 6, 9, 12, 15-pentaoxo-1, 4, 7, 10, 13-pentaazacyclopentadecan-2-yl)acetic acid |