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Aprepitant

Aprepitant

Item no.	A10083-10
Manufacturer	Adooq
CASRN	170729-80-3
Amount	10 mg
Quantity options	10 mg 10mM * 1mL in DMSO 2 mg 25 mg 5 mg
Category	Food Safety Drugs Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	>98%
Smiles	C[C&commat;H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C&commat;&commat;H]2[C&commat;&commat;H](N(CCO2)CC3=NC(=O)NN3)C4=CC=C(C=C4)F
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	MK0869, MK-869, L-754030, Emend
Similar products	Aprepitant
Available
Chemical Name	5-([(2R, 3S)-2-((R)-1-[3, 5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluorophenyl) morpholino]methyl)-1H-1, 2, 4-triazol-3(2H)-one
M. Wt.	534, 4
Short Description	Aprepitant is classified as an NK1 antagonist. Aprepitant has been shown to inhibit both the acute and delayed emesis induced by cytotoxic chemotherapeutic drugs by blocking substance P landing on receptors in the brains neurons. It has also been shown to increase the activity of the 5-HT3 receptor antagonists ondansetron and the corticosteroid dexamethasone, which are also used to prevent nausea and vomiting caused by chemotherapy.
Solubilty	DMSO
Storage	2 years at -20C

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

A10083-10-datasheet.pdf

A10083-10-safety-datasheet.pdf