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BAY 87-2243

BAY 87-2243

Item no.	M4869-10mM
Manufacturer	AbMole
CASRN	1227158-85-1
Amount	10mM*1mL
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	0,9886
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Target Information	HIF
Molecular Weight	525, 53
Solubility	DMSO 20 mg/mL
Bioactivity information	BAY87-2243 is a potent inhibitor of selective hypoxia-inducible facin-1 (HIF-1). Bay87-2243 induces iron death and necrosis in BRAFV600E melanoma cells by inhibiting the mitochondrial respiratory chain, resulting in ROS accumulation, lipid peroxidation, and GSH deletion.

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M4869-10mM-safety-datasheet.pdf