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S-Ruxolitinib

S-Ruxolitinib

Item no.	M3030-1mg
Manufacturer	AbMole
CASRN	941685-37-6
Amount	1mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	S-Ruxolitinib; INCB18424
Available
Target Information	JAK
Molecular Weight	306, 37
Solubility	DMSO 51 mg/mL
Bioactivity information	S-Ruxolitinib is the chirality of INCB018424, which is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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M3030-1mg-safety-datasheet.pdf