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AMD3465 hexahydrobromide（AMD3465 )

AMD3465 hexahydrobromide（AMD3465 )

Item no.	M2381-50mg
Manufacturer	AbMole
CASRN	185991-07-5
Amount	50mg
Category	Neuroscience Neural Lineage Markers Neuroinflammation Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	>98.0%
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	GENZ-644494 hexahydrobromide
Available
Target Information	CXCR
Molecular Weight	896, 07
Solubility	Water 95 mg/mL
Bioactivity information	AMD3465 hexahydrobromide（AMD3465 ) is an effective CXCR4 antagonist that inhibits 12G5 mAb in SupT1 cells. The IC50 values of CXCL12AF647 and CXCR4 were 0.75 nM and 18 nM, respectively. AMD 3465 also effectively inhibited X4 HIV replication (IC50, 1-10 nM), but not R5 HIV replication.

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M2381-50mg-safety-datasheet.pdf