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2-Methoxyestradiol

2-Methoxyestradiol

Manufacturer	AbMole
Category	Oncology Food Safety Hormones Neuroscience Neural Lineage Markers Inhibitors & Compound Libraries Small Molecules By Organ Breast Cancer Uterine, Ovarian & Cervical Cancer Neurodegeneration Markers
Type	Inhibitors
Specific against	other
Amount	50mg
Item no.	M1992-50mg
CASRN	362-07-2
eClass 6.1	30220300
eClass 9.0	32160605
Available
Alias	2ME2
Purity	0,9845
Target Information	HIF
Molecular Weight	302, 41
Solubility	DMSO ≥ 60 mg/mL
Bioactivity information	2-methoxyestradiol (2-ME2), an endogenous metabolite of 17β -estradiol (E2) with oral activity, is an apoptosis inducer and angiogenesis inhibitor with effective antitumor activity. Methoxyestradiol can also destabilize microtubules. Methoxyestradiol is a potent inhibitor of superoxide dismutase (SOD) and reactive oxygen species (ROS) that can induce autophagy in transformed cell line HEK293, cancer cell line U87 and HeLa.

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M1992-50mg-safety-datasheet.pdf