Background |
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Manufacturers Research Area |
Cancer, Invasion and Metastasis, Cell Biology Developmental Biology, Apoptosis, Caspases, Inhibition of Apoptosis, Ubiquitin, Ubiquitin-Proteasome Signaling Pathway, Death Receptor Signaling Pathway, Endocrine Metabolism, Immunology Inflammation |